Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13800984 | 0.90 | MAPT (0.44) | LMNATSHRCYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL283280 | 0.83 | ALDH1A1 (0.52) | LMNATSHRCYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL12350733 | 0.82 | TSHR (0.45) | LMNATSHRCYP1A2CYP2C19CYP3A4 | |
| SCHEMBL12536605 | 0.82 | ALDH1A1 (0.44) | TSHRCYP1A2ALDH1A1HSD17B10MAPT | |
| SCHEMBL27988043 | 0.81 | ALDH1A1 (0.53) | LMNATSHRCYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL12350752 | 0.77 | TSHR (0.46) | LMNATSHRCYP3A4ALDH1A1L3MBTL1 | |
| SCHEMBL12350740 | 0.76 | ALDH1A1 (0.47) | LMNATSHRCYP3A4ALDH1A1L3MBTL1 | |
| SCHEMBL28293724 | 0.76 | LMNA (0.50) | LMNATSHRCYP1A2CYP2C19CYP3A4 | |
| SCHEMBL5503949 | 0.75 | RAB9A (0.43) | LMNATSHRCYP1A2CYP2C19CYP3A4 | |
| SCHEMBL28529222 | 0.75 | RAB9A (0.65) | LMNATSHRCYP1A2CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070989-A1 | METAL-CHELATE AZO DYE AND OPTICAL RECORDING MEDIUM | Mitsubishi Kagaku Media Co., Ltd. (JP) | 2009-06-17 | — | — | EP | disclosed |