SCHEMBL13801153

SCHEMBL13801153

c1nnc(-c2ccc(-c3nc4sc(-c5ccc(-c6nnco6)cc5)nc4s3)cc2)o1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 10/20 0.55
LMNA P02545 3/20 0.47
ALDH1A1 P00352 2/20 0.47
MAPT P10636 2/20 0.47
HTT P42858 2/20 0.47
KDM4E B2RXH2 2/20 0.47
TLR8 Q9NR97 1/20 0.47
CDC7 O00311 1/20 0.47
DBF4 Q9UBU7 1/20 0.47
HPGD P15428 2/20 0.46
MAPK1 P28482 1/20 0.46
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
TSHR P16473 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17694561 0.80 NOTUM (0.78) NOTUMLMNAALDH1A1MAPTHTT
SCHEMBL2610163 0.78 NOTUM (0.75) NOTUMLMNAALDH1A1MAPTHTT
SCHEMBL860256 0.71 NOTUM (0.64) NOTUMLMNAALDH1A1MAPTHTT
SCHEMBL19356867 0.71 NOTUM (0.64) NOTUMLMNAALDH1A1MAPTHTT
SCHEMBL5571187 0.71 NOTUM (0.91) NOTUMLMNAALDH1A1MAPTHTT
SCHEMBL3685411 0.71 NOTUM (0.64) NOTUMLMNAALDH1A1MAPTHTT
SCHEMBL14814390 0.71 NOTUM (1.00) NOTUMLMNAALDH1A1MAPTHTT
SCHEMBL9096052 0.71 NOTUM (0.64) NOTUMLMNAALDH1A1MAPTHTT
SCHEMBL3537328 0.71 NOTUM (1.00) NOTUMLMNAALDH1A1MAPTHTT
SCHEMBL368913 0.71 NOTUM (0.64) NOTUMLMNAALDH1A1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090156827-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS AND ORGANIC ELECTROLUMINESCENT ELEMENT TOYO INK MFG. CO., LTD. (JP) 2009-06-18 US disclosed
US-20090156827-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS AND ORGANIC ELECTROLUMINESCENT ELEMENT TOYO INK MFG. CO., LTD. (JP) 2009-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156827-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS AND ORGANIC ELECTROLUMINESCENT ELEMENT ELP1, ELAVL1, ELF3 NOTUM 3406/4885LMNA 1330/4885ALDH1A1 1089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.