⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14064163 | 0.85 | — | — | |
| SCHEMBL12292453 | 0.80 | — | — | |
| SCHEMBL19890099 | 0.78 | HSD17B10 (0.31) | — | |
| SCHEMBL10087269 | 0.77 | — | — | |
| SCHEMBL10048289 | 0.77 | — | — | |
| SCHEMBL20343302 | 0.76 | — | — | |
| SCHEMBL4342842 | 0.74 | ADRB2 (0.33) | — | |
| SCHEMBL21178189 | 0.73 | CA1 (0.34) | — | |
| SCHEMBL7572703 | 0.72 | LMNA (0.30) | — | |
| SCHEMBL14316421 | 0.71 | MAOA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3439703-B1 | NUCLEIC ACID LINKED TO A TRIVALENT GLYCOCONJUGATE | SILENCE THERAPEUTICS GMBH (DE) | 2020-04-29 | — | — | EP | disclosed |
| WO-2017174657-A1 | NUCLEIC ACID LINKED TO A TRIVALENT GLYCOCONJUGATE | SILENCE THERAPEUTICS GMBH (DE) | 2017-10-12 | — | — | WO | disclosed |
| US-20120322991-A1 | Compositions and methods for selective delivery of oligonucleotide molecules to specific neuron types | NLIFE THERAPEUTICS, S.L. (ES) | 2012-12-20 | — | — | US | disclosed |
| US-7541448-B2 | Oligonucleotides containing molecular rods | ROCHE DIAGNOSTIS OPERATIONS, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| EP-1538221-B1 | Oligonucleotides containing molecular rods | ROCHE DIAGNOSTICS GMBH (DE) | 2008-05-07 | — | — | EP | disclosed |