Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14064163 | 0.80 | — | — | |
| SCHEMBL19890099 | 0.79 | HSD17B10 (0.31) | — | |
| SCHEMBL386368 | 0.78 | LMNA (0.30) | LMNA | |
| SCHEMBL4342842 | 0.75 | ADRB2 (0.33) | — | |
| SCHEMBL1391357 | 0.74 | — | — | |
| SCHEMBL3624139 | 0.74 | — | — | |
| SCHEMBL15314806 | 0.74 | — | — | |
| SCHEMBL21178189 | 0.74 | CA1 (0.34) | — | |
| SCHEMBL21178019 | 0.72 | SPHK1 (0.37) | — | |
| SCHEMBL21178108 | 0.72 | SPHK1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025047679-A1 | STABLE TARGET EDITING GUIDE RNA HAVING PHOSPHATE MOIETY MODIFICATION INTRODUCED THEREINTO | 学校法人福岡大学 | 2025-03-06 | — | — | WO | disclosed |
| US-11787833-B2 | Modified cyclic dinucleoside compounds as sting modulators | ALIGOS THERAPEUTICS, INC. (US) | 2023-10-17 | — | — | US | disclosed |
| US-11787833-B2 | Modified cyclic dinucleoside compounds as sting modulators | ALIGOS THERAPEUTICS, INC. (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230303614-A1 | CAPPING COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | SEATTLE PROJECT CORP. | 2023-09-28 | — | — | US | disclosed |
| US-20230119227-A1 | OLIGONUCLEOTIDE SYNTHESIS ON SOLID SUPPORT | INTEGRATED DNA TECHNOLOGIES, INC. | 2023-04-20 | — | — | US | disclosed |
| EP-4110789-A1 | OLIGONUCLEOTIDE SYNTHESIS ON SOLID SUPPORT | Integrated Dna Technologies, Inc. (US) | 2023-01-04 | — | — | EP | disclosed |
| US-20200369711-A1 | MODIFIED CYCLIC DINUCLEOSIDE COMPOUNDS AS STING MODULATORS | ALIGOS THERAPEUTICS, INC. | 2020-11-26 | — | — | US | disclosed |
| US-20200369703-A1 | Modified oligonucleotides and compound that can be used for synthesizing same | GUANGZHOU RIBOBIO CO LTD (CN) | 2020-11-26 | — | — | US | disclosed |
| US-20190112328-A1 | DIARYLSULFIDE BACKBONE CONTAINING PHOTOLABILE PROTECTING GROUPS | NIMBLEGEN SYSTEMS GMBH (DE) | 2019-04-18 | — | — | US | disclosed |
| EP-2696679-B1 | 2'-CYANO SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME (US) | 2017-08-02 | — | — | EP | disclosed |
| WO-2012142093-A2 | 2'-CYANO SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME CORP. (US) | 2012-10-18 | — | — | WO | disclosed |
| EP-0751948-B1 | NOVEL PHOSPHORAMIDATE AND PHOPHOROTHIOAMIDATE OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS INC (US) | 2002-09-25 | — | — | EP | disclosed |
| US-5717083-A | COMPLEXING WITH PROTEINS, NUCLEIC ACIDS, LIPIDS | ISIS PHARMACEUTICALS, INC. (US) | 1998-02-10 | — | — | US | disclosed |
| US-5637684-A | BINDING PROTEINS, NUCLEIC ACIDS, LIPIDS; PHOSPHOLIPASE INHIBITOR | ISIS PHARMACEUTICALS, INC. (US) | 1997-06-10 | — | — | US | disclosed |
| EP-0751948-A4 | NOVEL PHOSPHORAMIDATE AND PHOPHOROTHIOAMIDATE OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS INC (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0751948-A1 | NOVEL PHOSPHORAMIDATE AND PHOPHOROTHIOAMIDATE OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 1997-01-08 | — | — | EP | disclosed |
| WO-1996029337-A1 | THIONO TRIESTER MODIFIED ANTISENSE OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATES | HYBRIDON, INC. (US) | 1996-09-26 | — | — | WO | disclosed |
| WO-1995023160-A1 | NOVEL PHOSPHORAMIDATE AND PHOPHOROTHIOAMIDATE OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 1995-08-31 | — | — | WO | disclosed |
| EP-0229053-A1 | METHOD FOR SYNTHESIZING DEOXYOLIGONUCLEOTIDES | UNIVERSITY PATENTS, INC. (US) | 1987-07-22 | — | — | EP | disclosed |
| WO-1986007362-A1 | METHOD FOR SYNTHESIZING DEOXYOLIGONUCLEOTIDES | UNIVERSITY PATENTS, INC. (US) | 1986-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303614-A1 | CAPPING COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | RNGTT, RNMT, NSUN2 | LMNA 1820/4885 |
| US-20200369703-A1 | Modified oligonucleotides and compound that can be used for synthesizing same | POLRMT, RNASE1, ADAR | LMNA 1108/4885 |
| US-20200369711-A1 | MODIFIED CYCLIC DINUCLEOSIDE COMPOUNDS AS STING MODULATORS | STING1, CGAS, IRF3 | LMNA 825/4885 |
| US-20190112328-A1 | DIARYLSULFIDE BACKBONE CONTAINING PHOTOLABILE PROTECTING GROUPS | CRY2, PRXL2A, MGMT | LMNA 2105/4885 |
| US-11787833-B2 | Modified cyclic dinucleoside compounds as sting modulators | STING1, CGAS, IRF3 | LMNA 825/4885 |
| US-20230119227-A1 | OLIGONUCLEOTIDE SYNTHESIS ON SOLID SUPPORT | RNGTT, SSU72, NSUN2 | LMNA 1861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.