SCHEMBL13802251

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10909072	0.92	PTGS2 (0.83)	PTGS2HIF1APTGS1GLO1HTR1A
	Acemetacin SCHEMBL29402955	0.91	PTGS2 (1.00)	PTGS2HIF1APTGS1GLO1HTR1A
	SCHEMBL10519250	0.91	PTGS2 (0.82)	PTGS2HIF1APTGS1GLO1HTR1A
	Acemetacin SCHEMBL23843	0.91	PTGS2 (1.00)	PTGS2HIF1APTGS1GLO1HTR1A
	Acemetacin SCHEMBL10910170	0.90	PTGS2 (0.98)	PTGS2HIF1APTGS1GLO1HTR1A
	Acemetacin SCHEMBL5400266	0.90	PTGS2 (0.98)	PTGS2HIF1APTGS1GLO1HTR1A
	SCHEMBL12747878	0.90	AKR1C3 (0.89)	PTGS2HIF1APTGS1GLO1HTR1A
	Acemetacin SCHEMBL5306430	0.89	PTGS2 (0.96)	PTGS2HIF1APTGS1GLO1HTR1A
	SCHEMBL10516272	0.89	AKR1C3 (0.82)	PTGS2HIF1APTGS1GLO1HTR1A
	SCHEMBL10516567	0.87	PTGS2 (0.79)	PTGS2HIF1APTGS1GLO1HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.