Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL138875 | 0.86 | CYP3A4 (0.75) | RAB9ACYP3A4ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL29642680 | 0.86 | CYP3A4 (0.75) | RAB9ACYP3A4ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL3944098 | 0.86 | CYP3A4 (0.75) | RAB9ACYP3A4ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL13802497 | 0.86 | AGBL2 (0.60) | RAB9ASLC13A5CYP3A4ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL8838333 | 0.85 | CYP3A4 (0.73) | RAB9ACYP3A4ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL7332204 | 0.85 | CYP3A4 (0.73) | RAB9ACYP3A4ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL18392739 | 0.80 | CYP3A4 (0.52) | RAB9ASLC13A5CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL2957608 | 0.79 | CYP3A4 (0.65) | RAB9ACYP3A4ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL7015047 | 0.79 | ALDH1A1 (0.49) | RAB9ASLC13A5CYP3A4ALDH1A1CYP1A2 | |
| Piperonylic Acid SCHEMBL3936749 | 0.78 | ALDH1A1 (0.73) | RAB9ACYP3A4ALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | APP, PSEN2, PSEN1 | RAB9A 3268/4885SLC13A5 2507/4885CYP3A4 1396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.