Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.51 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13802498 | 0.86 | RAB9A (0.63) | AGBL2ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL29642680 | 0.82 | CYP3A4 (0.75) | AGBL2ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL138875 | 0.82 | CYP3A4 (0.75) | AGBL2ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL3944098 | 0.82 | CYP3A4 (0.75) | AGBL2ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL16675752 | 0.81 | FYN (0.59) | CYP3A4GABRA1GABRB2PTGS2CNR1 | |
| Hydrochloric Acid SCHEMBL8838333 | 0.81 | CYP3A4 (0.73) | AGBL2ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7332204 | 0.81 | CYP3A4 (0.73) | AGBL2ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL28032595 | 0.79 | LMNA (0.63) | CYP1A2CYP2C19GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2929152 | 0.78 | CALM1 (0.46) | ALDH1A1CYP1A2CYP3A4CYP2C19RAB9A | |
| SCHEMBL18015825 | 0.78 | MAPT (0.55) | ALDH1A1RAB9AGABRA1GABRB2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | APP, PSEN2, PSEN1 | AGBL2 1600/4885ALDH1A1 2808/4885CYP1A2 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.