Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.51 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | NEU3 | Q9UQ49 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PTGFR | P43088 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PLEC | Q15149 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3946930 | 0.85 | HCAR3 (0.50) | HCAR3CDC25BNEU3L3MBTL1PKM | |
| SCHEMBL9190020 | 0.82 | HCAR3 (0.55) | HCAR3CDC25BNEU3L3MBTL1PKM | |
| SCHEMBL3947534 | 0.82 | HCAR3 (0.48) | HCAR3CDC25BNEU3L3MBTL1PKM | |
| SCHEMBL5405584 | 0.80 | CDC25B (0.53) | CDC25BNEU3L3MBTL1PKMNPSR1 | |
| SCHEMBL2890452 | 0.77 | HCAR3 (0.61) | HCAR3NEU3L3MBTL1HTTKDM4E | |
| Hydrochloric Acid SCHEMBL8815251 | 0.77 | SLC9A1 (0.62) | — | |
| SCHEMBL3952762 | 0.77 | SMN1; SMN2 (0.64) | L3MBTL1HTTALDH1A1MAPTNPC1 | |
| SCHEMBL9196477 | 0.77 | HCAR3 (0.58) | HCAR3NPSR1KDM4EALDH1A1GAA | |
| SCHEMBL9196904 | 0.77 | L3MBTL1 (0.50) | L3MBTL1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL6801964 | 0.77 | NPSR1 (0.43) | HCAR3CDC25BNEU3L3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544676-B2 | Sulfamoyl benzamides and methods of their use | ADOLOR CORPORATION (US) | 2009-06-09 | — | — | US | disclosed |
| US-20080058302-A1 | Sulfamoyl Benzamides and Methods of Their Use | CALIXA THERAPEUTICS, INC. | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058302-A1 | Sulfamoyl Benzamides and Methods of Their Use | CNR2, TRPV1, CNR1 | HCAR3 376/4885CDC25B 1703/4885NEU3 3304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.