Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | OGG1 | O15527 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.62 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 9/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | F10 | P00742 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5935569 | 0.85 | MAPT (0.79) | HDAC1HDAC8HDAC6OGG1ALDH1A1 | |
| SCHEMBL1886020 | 0.80 | HDAC1 (1.00) | HDAC1HDAC8HDAC6OGG1ALDH1A1 | |
| SCHEMBL7984062 | 0.78 | HDAC1 (0.79) | HDAC1HDAC8HDAC6OGG1ALDH1A1 | |
| SCHEMBL6477287 | 0.78 | OGG1 (1.00) | HDAC1HDAC8HDAC6OGG1ALDH1A1 | |
| SCHEMBL16562057 | 0.78 | MAPT (0.72) | ALDH1A1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL14096502 | 0.78 | ALDH1A1 (0.72) | HDAC1HDAC8HDAC6OGG1ALDH1A1 | |
| SCHEMBL444722 | 0.77 | MCL1 (1.00) | HDAC1HDAC8HDAC6OGG1ALDH1A1 | |
| SCHEMBL29911721 | 0.77 | MCL1 (1.00) | HDAC1HDAC8HDAC6OGG1ALDH1A1 | |
| SCHEMBL11177633 | 0.76 | MCL1 (0.72) | HDAC1HDAC8HDAC6OGG1ALDH1A1 | |
| SCHEMBL4651922 | 0.76 | MAPT (0.78) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070533-A1 | METHODS OF INHIBITING STEROYL COA DESATURASE | COMPLEGEN, INC. (US) | 2009-06-04 | — | — | WO | disclosed |