Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20363911 | 0.85 | NPC1 (0.64) | NPC1RAB9AHTTLMNAPOLB | |
| SCHEMBL28547709 | 0.81 | CA1 (0.54) | NPC1RAB9AHTTLMNAPOLB | |
| SCHEMBL28543727 | 0.81 | NPC1 (0.46) | NPC1RAB9AHTTLMNAPOLB | |
| SCHEMBL1098519 | 0.81 | RAB9A (0.46) | NPC1RAB9AHTTLMNAPOLB | |
| SCHEMBL9408768 | 0.80 | NPC1 (0.45) | NPC1RAB9AHTTLMNAPOLB | |
| SCHEMBL28897022 | 0.80 | NPC1 (0.47) | NPC1RAB9AHTTLMNAPOLB | |
| SCHEMBL31558927 | 0.80 | ALDH1A1 (0.48) | NPC1RAB9AHTTLMNAPOLB | |
| SCHEMBL563559 | 0.78 | RAB9A (0.64) | NPC1RAB9AHTTLMNAPOLB | |
| SCHEMBL29768260 | 0.78 | RAB9A (0.64) | NPC1RAB9AHTTLMNAPOLB | |
| SCHEMBL28547204 | 0.78 | IDH1 (0.44) | NPC1RAB9AHTTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090162541-A1 | NEAR-INFRARED-ABSORBING MATERIAL | FUJIFILM CORPORATION (JP) | 2009-06-25 | — | — | US | disclosed |
| US-20090117266-A1 | NEAR-INFRARED-ABSORBING MATERIAL | FUJIFILM CORPORATION (JP) | 2009-05-07 | — | — | US | disclosed |
| US-20080169453-A1 | Near infrared ray absorbing material and near infrared ray absorbing filter | FUJIFILM CORPORATION (JP) | 2008-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080169453-A1 | Near infrared ray absorbing material and near infrared ray absorbing filter | RRP12, MRPS22, H1-10 | NPC1 783/4885RAB9A 2312/4885HTT 3363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.