Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1098570 | 0.89 | ALDH1A1 (0.43) | RAB9ANPC1HTTLMNAPOLB | |
| SCHEMBL9408768 | 0.88 | NPC1 (0.45) | RAB9ANPC1HTTLMNAPOLB | |
| SCHEMBL1099556 | 0.87 | NPC1 (0.42) | RAB9ANPC1LMNAPOLBKDM4E | |
| SCHEMBL1100125 | 0.86 | NPC1 (0.39) | RAB9ANPC1LMNAPOLBKDM4E | |
| SCHEMBL1100175 | 0.86 | KDM4E (0.35) | RAB9ANPC1HTTLMNAKDM4E | |
| SCHEMBL28547204 | 0.85 | IDH1 (0.44) | RAB9ANPC1HTTLMNAPOLB | |
| SCHEMBL1100542 | 0.83 | CACNA1D (0.38) | KDM4E | |
| SCHEMBL2146554 | 0.81 | NPC1 (0.64) | RAB9ANPC1LMNAPOLBKDM4E | |
| SCHEMBL13808306 | 0.81 | NPC1 (0.49) | RAB9ANPC1HTTLMNAPOLB | |
| SCHEMBL1100484 | 0.79 | NPC1 (0.38) | RAB9ANPC1HTTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102203072-B | Uv/visible light absorbers for ophthalmic lens materials | ALCON INC | 2014-08-13 | — | — | CN | disclosed |
| EP-2346840-B1 | UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | NOVARTIS AG (CH) | 2013-12-25 | — | — | EP | disclosed |
| US-8232326-B2 | UV/visible light absorbers for ophthalmic lens materials | NOVARTIS AG (CH) | 2012-07-31 | — | — | US | disclosed |
| US-20120142877-A1 | UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | NOVARTIS AG (CH) | 2012-06-07 | — | — | US | disclosed |
| US-8153703-B2 | UV/visible light absorbers for ophthalmic lens materials | NOVARTIS AG (CH) | 2012-04-10 | — | — | US | disclosed |
| CN-102203072-A | Uv/visible light absorbers for ophthalmic lens materials | ALCON INC | 2011-09-28 | — | — | CN | disclosed |
| EP-2346840-A1 | UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | Alcon, Inc. (CH) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010053917-A1 | UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | ALCON, INC. (CH) | 2010-05-14 | — | — | WO | disclosed |
| US-20100113641-A1 | UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | ALCON, INC. (CH) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113641-A1 | UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | UACA, CRYZ, CRYAA | RAB9A 4701/4885NPC1 3813/4885HTT 581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.