Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1098519 | 0.88 | RAB9A (0.46) | NPC1RAB9AHTTLMNAPOLB | |
| SCHEMBL28547204 | 0.84 | IDH1 (0.44) | NPC1RAB9AHTTLMNAPOLB | |
| SCHEMBL9408866 | 0.84 | NPC1 (0.40) | NPC1RAB9AHTTLMNAPOLB | |
| SCHEMBL508460 | 0.82 | NPC1 (0.62) | NPC1RAB9ALMNAPOLBKDM4E | |
| Hydrochloric Acid SCHEMBL8372133 | 0.81 | NPC1 (0.61) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL9408798 | 0.80 | NPC1 (0.49) | NPC1RAB9AHTTLMNAPOLB | |
| SCHEMBL13808306 | 0.80 | NPC1 (0.49) | NPC1RAB9AHTTLMNAPOLB | |
| SCHEMBL9408769 | 0.79 | NPC1 (0.51) | NPC1RAB9AHTTLMNAPOLB | |
| SCHEMBL9408834 | 0.78 | NPC1 (0.45) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL9408808 | 0.78 | NPC1 (0.43) | NPC1RAB9ALMNAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593936-A1 | N-[2-hydroxy-3-(2H-benzotriazol-2-yl)benzyl]oxamides as light stabilisers | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-04-27 | — | — | EP | disclosed |