Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29337015 | 0.82 | SMN1; SMN2 (0.36) | ALDH1A1TDP1GAAKDM4EMAPT | |
| SCHEMBL17903269 | 0.80 | ALDH1A1 (0.34) | ALDH1A1TDP1MAPK1GAANPSR1 | |
| SCHEMBL19300441 | 0.79 | AKT1 (0.38) | ALDH1A1TDP1MAPK1TSHRAKT1 | |
| SCHEMBL17903259 | 0.78 | TDP1 (0.33) | ALDH1A1TDP1MAPK1GAANPSR1 | |
| SCHEMBL13341222 | 0.77 | CHRM2 (0.34) | ALDH1A1TDP1NPSR1TSHRKDM4E | |
| SCHEMBL22930883 | 0.77 | RAB9A (0.49) | ALDH1A1NPSR1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL23183270 | 0.76 | ATM (0.41) | ALDH1A1MAPK1NPSR1AKT1MAPT | |
| SCHEMBL19101609 | 0.74 | TSHR (0.32) | ALDH1A1TDP1MAPK1GAANPSR1 | |
| SCHEMBL21253891 | 0.72 | AKT1 (0.37) | ALDH1A1TDP1MAPK1TSHRAKT1 | |
| SCHEMBL19046658 | 0.72 | AKT1 (0.37) | ALDH1A1TDP1MAPK1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009073911-A1 | TREATMENT AND PROPHYLAXIS | MATER MEDICAL RESEARCH INSTITUTE (AU) | 2009-06-18 | — | — | WO | disclosed |