Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24631062 | 0.81 | SMN1; SMN2 (0.34) | SMN1; SMN2NPC1RAB9APOLBGAA | |
| SCHEMBL19495183 | 0.80 | GAA (0.40) | SMN1; SMN2RAB9APOLBGAAMAOA | |
| SCHEMBL8334918 | 0.74 | CES2 (0.39) | SMN1; SMN2NPC1RAB9APOLBGAA | |
| SCHEMBL21428975 | 0.69 | CES2 (0.35) | SMN1; SMN2NPC1RAB9APOLBGAA | |
| SCHEMBL22930883 | 0.68 | RAB9A (0.49) | SMN1; SMN2NPC1RAB9ACES2CES1 | |
| SCHEMBL22172432 | 0.64 | MAOA (0.45) | NPC1RAB9ACES2CES1MAOA | |
| SCHEMBL24038413 | 0.64 | TGM2 (0.38) | SMN1; SMN2NPC1RAB9APOLBGAA | |
| SCHEMBL21690150 | 0.63 | PLK1 (0.46) | SMN1; SMN2NPC1RAB9ACES2CES1 | |
| SCHEMBL14094958 | 0.63 | LMNA (0.36) | SMN1; SMN2POLBCES2CES1METTL3 | |
| SCHEMBL14095076 | 0.61 | CES2 (0.35) | SMN1; SMN2NPC1RAB9APOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239795-A1 | NOVEL AZAINDOLE DERIVATIVES AS ANTIVIRAL AGENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239795-A1 | NOVEL AZAINDOLE DERIVATIVES AS ANTIVIRAL AGENTS | AXL, ABL1, ZC3HAV1 | SMN1; SMN2 3877/4885NPC1 4239/4885RAB9A 1480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.