Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | F12 | P00748 | 1/20 | 0.31 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19300441 | 0.79 | AKT1 (0.38) | AKT1CES1ALDH1A1CES2DAO | |
| SCHEMBL19046658 | 0.77 | AKT1 (0.37) | AKT1ALDH1A1DAOTSHRNAPRT | |
| SCHEMBL24975608 | 0.77 | AKT1 (0.33) | AKT1CES1ALDH1A1CES2DAO | |
| SCHEMBL24884816 | 0.76 | AKT1 (0.35) | AKT1CES1ALDH1A1CES2DAO | |
| SCHEMBL20625867 | 0.75 | MEN1 (0.32) | AKT1MAPK1ATMNFE2L2MEN1 | |
| SCHEMBL21242007 | 0.73 | KDM1A (0.41) | AKT1CES1ALDH1A1CES2DAO | |
| SCHEMBL23183270 | 0.72 | ATM (0.41) | AKT1CES1ALDH1A1CES2MAPK1 | |
| SCHEMBL22988641 | 0.72 | KMT2A (0.37) | AKT1CES1ALDH1A1CES2DAO | |
| SCHEMBL22071486 | 0.72 | CES2 (0.34) | AKT1CES1ALDH1A1CES2MAPK1 | |
| SCHEMBL13808632 | 0.72 | ALDH1A1 (0.34) | AKT1CES1ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150606-B1 | BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLES CARRYING BENZOFURANE OR BENZOTHIOPHENE GROUPS FOR ORGANIC LIGHT EMITTING DIODES | IDEMITSU KOSAN CO (JP) | 2019-08-14 | — | — | EP | disclosed |