Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 7/20 | 0.49 |
| ▸ | GSTO1 | P78417 | 9/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TGM1 | P22735 | 1/20 | 0.37 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1694410 | 0.79 | DAO (0.52) | RAF1DAOLMNA | |
| SCHEMBL26584978 | 0.77 | DAO (0.43) | TGM2GSTO1DAOF13A1LMNA | |
| SCHEMBL11471040 | 0.77 | HSD17B10 (0.48) | RAF1DAOLMNA | |
| SCHEMBL8031103 | 0.73 | TSHR (0.44) | RAF1DAOPI4KBLMNA | |
| SCHEMBL7289853 | 0.71 | ALDH1A1 (0.49) | RAF1DAOLMNAEGFR | |
| SCHEMBL29183917 | 0.70 | CYP1A2 (0.51) | RAF1LMNA | |
| SCHEMBL28196751 | 0.70 | RAF1 (0.46) | RAF1DAO | |
| SCHEMBL28196767 | 0.70 | GAA (0.54) | RAF1DAOLMNA | |
| SCHEMBL28114474 | 0.69 | TGM2 (0.66) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL1352029 | 0.69 | RAF1 (0.48) | RAF1DAOPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4828407-B2 | — | — | 2011-11-30 | — | — | JP | claimed |
| EP-1594869-A2 | 3-SUBSTITUTED-2(ARYLALKYL)-1-AZABICYCLOALKANES AND METHODS OF USE THEREOF | Targacept, Inc. (US) | 2005-11-16 | — | — | EP | claimed |
| WO-2004076449-A2 | 3-SUBSTITUTED-2(ARYLALKYL)-1-AZABICYCLOALKANES AND METHODS OF USE THEREOF | TARGACEPT, INC. (US) | 2004-09-10 | — | — | WO | claimed |
| EP-1594869-A2 | 3-SUBSTITUTED-2(ARYLALKYL)-1-AZABICYCLOALKANES AND METHODS OF USE THEREOF | Targacept, Inc. (US) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004076449-A2 | 3-SUBSTITUTED-2(ARYLALKYL)-1-AZABICYCLOALKANES AND METHODS OF USE THEREOF | TARGACEPT, INC. (US) | 2004-09-10 | — | — | WO | disclosed |