Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | FADS1 | O60427 | 2/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812611 | 0.86 | P2RX1 (0.66) | P2RX1P2RX4P2RX7MAOAMAOB | |
| SCHEMBL13812554 | 0.83 | MEN1 (0.59) | P2RX1MAPTTSHRNPSR1ALDH1A1 | |
| SCHEMBL13189711 | 0.83 | P2RX1 (0.65) | P2RX1P2RX4P2RX7FADS1MEN1 | |
| SCHEMBL13812610 | 0.82 | P2RX1 (0.61) | P2RX1P2RX4P2RX7MAOAMAOB | |
| SCHEMBL13812595 | 0.81 | P2RX1 (0.60) | P2RX1P2RX4P2RX7MAOAMAOB | |
| SCHEMBL13812651 | 0.81 | P2RX1 (0.62) | P2RX1P2RX4P2RX7FADS1TMPRSS4 | |
| SCHEMBL13812633 | 0.81 | P2RX1 (0.59) | P2RX1P2RX4P2RX7MAOAMAOB | |
| SCHEMBL13189702 | 0.80 | NPC1 (0.70) | P2RX1MAPTTSHRNPSR1ALDH1A1 | |
| SCHEMBL13812632 | 0.79 | P2RX1 (0.60) | P2RX1P2RX4P2RX7FADS1TMPRSS4 | |
| SCHEMBL13189709 | 0.77 | FADS1 (0.82) | P2RX1MAPTTSHRALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |