Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | FADS1 | O60427 | 1/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3881082 | 0.89 | FADS1 (0.56) | MAPTGAAPOLBTP53THRB | |
| SCHEMBL13812570 | 0.82 | TMPRSS4 (0.69) | MEN1KMT2AFADS1TMPRSS4P2RX1 | |
| SCHEMBL13812580 | 0.80 | TMPRSS4 (0.69) | MEN1KMT2AFADS1TMPRSS4P2RX1 | |
| SCHEMBL18341186 | 0.78 | LRRK2 (0.60) | GAALRRK2TMPRSS4P2RX1P2RX4 | |
| SCHEMBL13189711 | 0.77 | P2RX1 (0.65) | MEN1KMT2AFADS1LRRK2TMPRSS4 | |
| SCHEMBL13812621 | 0.76 | P2RX1 (0.67) | FADS1TMPRSS4P2RX1P2RX4P2RX7 | |
| SCHEMBL13812556 | 0.76 | P2RX1 (0.60) | FADS1TMPRSS4P2RX1P2RX4P2RX7 | |
| SCHEMBL13812875 | 0.75 | KCNMA1 (0.59) | MAPTGAATP53MEN1KMT2A | |
| SCHEMBL13812571 | 0.75 | FADS1 (0.53) | MAPTTP53FADS1TMPRSS4P2RX1 | |
| SCHEMBL13812558 | 0.75 | P2RX1 (0.59) | FADS1TMPRSS4P2RX1P2RX4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |