Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.55 |
| ▸ | TUBB | P07437 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.49 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812667 | 0.89 | PTGS1 (0.56) | KMT2ASGMS2TUBBMEN1LMNA | |
| SCHEMBL13812659 | 0.89 | KMT2A (0.53) | KMT2ATUBBMEN1MAPTLMNA | |
| SCHEMBL13812594 | 0.83 | TUBB (0.64) | KMT2ASGMS2TUBBMEN1MAPT | |
| SCHEMBL6355276 | 0.83 | KMT2A (0.63) | KMT2ASGMS2TP53SMN1; SMN2LMNA | |
| SCHEMBL13812617 | 0.82 | RAB9A (0.60) | KMT2ATUBBMEN1MAPTTP53 | |
| SCHEMBL13236587 | 0.81 | TUBB (0.75) | KMT2ATUBBMEN1MAPTTP53 | |
| SCHEMBL30100461 | 0.81 | TUBB (0.75) | KMT2ATUBBMEN1MAPTTP53 | |
| SCHEMBL6360998 | 0.81 | KMT2A (0.60) | KMT2ASGMS2MEN1MAPTTP53 | |
| SCHEMBL6356805 | 0.81 | KMT2A (0.60) | KMT2ASGMS2MEN1TP53SMN1; SMN2 | |
| SCHEMBL13812613 | 0.79 | DNMT3A (0.55) | KMT2ATUBBMEN1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |