Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812663 | 0.89 | KMT2A (0.59) | KMT2AMEN1TDP1AKR1C3LMNA | |
| SCHEMBL13812613 | 0.86 | DNMT3A (0.55) | PTGS1KMT2AMEN1TDP1AKR1C3 | |
| SCHEMBL13812664 | 0.84 | PTGS1 (0.58) | PTGS1KMT2AMEN1TDP1CDK1 | |
| SCHEMBL13812597 | 0.83 | THRB (0.58) | PTGS1KMT2AMEN1TDP1CDK1 | |
| SCHEMBL13812638 | 0.83 | NPC1 (0.54) | PTGS1KMT2AMEN1TDP1CDK1 | |
| SCHEMBL13812659 | 0.80 | KMT2A (0.53) | PTGS1KMT2AMEN1TDP1CDK1 | |
| SCHEMBL13812875 | 0.77 | KCNMA1 (0.59) | KMT2AMEN1TDP1GAAHTT | |
| SCHEMBL13812596 | 0.77 | THRB (0.58) | PTGS1KMT2AMEN1TDP1CDK1 | |
| SCHEMBL13812594 | 0.76 | TUBB (0.64) | KMT2AMEN1LMNAHTTMCL1 | |
| SCHEMBL6357661 | 0.76 | SGMS2 (0.52) | KMT2AMEN1TDP1AKR1C3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |