Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812670 | 0.89 | NR1H4 (0.48) | NR1H4KMT2AMEN1SIRT2NPC1 | |
| SCHEMBL13812798 | 0.86 | G6PD (0.48) | KMT2AMEN1RAB9AP2RX1MAPT | |
| SCHEMBL3863657 | 0.85 | P2RX1 (0.62) | NR1H4KMT2AMEN1SIRT2NPC1 | |
| SCHEMBL13812764 | 0.82 | LRRK2 (0.55) | NR1H4KMT2AMEN1SIRT2MAPT | |
| SCHEMBL13812584 | 0.81 | MEN1 (0.53) | NR1H4KMT2AMEN1SIRT2NPC1 | |
| SCHEMBL27782904 | 0.81 | KDM1A (0.64) | KMT2AMEN1P2RX1MAPTKDM1A | |
| SCHEMBL13812642 | 0.80 | P2RX1 (0.61) | NR1H4KMT2AMEN1SIRT2NPC1 | |
| SCHEMBL13812550 | 0.79 | SIRT2 (0.52) | NR1H4KMT2AMEN1SIRT2NPC1 | |
| SCHEMBL13812562 | 0.79 | TMPRSS4 (0.62) | NR1H4KMT2AMEN1SIRT2NPC1 | |
| SCHEMBL13812552 | 0.78 | SIRT2 (0.52) | NR1H4KMT2AMEN1SIRT2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |