Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812930 | 0.90 | G6PD (0.49) | G6PDCRHBPCRHR2HTTMAPT | |
| SCHEMBL13812763 | 0.88 | GRM5 (0.53) | HTTMAPTMEN1KMT2APOLB | |
| SCHEMBL13812799 | 0.86 | NR1H4 (0.50) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL13812801 | 0.85 | GRM5 (0.48) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL13812800 | 0.84 | KDM4E (0.50) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL13812560 | 0.81 | P2RX1 (0.56) | MAPTMEN1KMT2APOLBGRM5 | |
| SCHEMBL13812931 | 0.81 | ALDH1A1 (0.49) | HTTMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13812737 | 0.81 | RAB9A (0.66) | HTTMAPTMEN1KMT2APKM | |
| SCHEMBL13812742 | 0.80 | KCNK3 (0.56) | MAPTKMT2ASMN1; SMN2POLBRAB9A | |
| SCHEMBL13812948 | 0.79 | FADS1 (0.50) | MAPTMEN1KMT2APOLBGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |