Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 11/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812803 | 0.90 | TRPV1 (0.50) | TP53MAPTKCNK3KCNK9 | |
| SCHEMBL13812809 | 0.89 | POLB (0.51) | TP53MAPTKCNK3KCNK9 | |
| SCHEMBL13812936 | 0.88 | FADS1 (0.49) | LMNATP53MAPTKCNK3KCNK9 | |
| SCHEMBL13812946 | 0.87 | FADS1 (0.54) | P2RX1TMPRSS4P2RX4P2RX7LMNA | |
| SCHEMBL13812934 | 0.87 | KCNK3 (0.47) | LMNATP53KCNK3KCNK9 | |
| SCHEMBL13812942 | 0.87 | POLB (0.50) | TP53KCNK3KCNK9 | |
| SCHEMBL13812948 | 0.86 | FADS1 (0.50) | P2RX1TMPRSS4P2RX4P2RX7LMNA | |
| SCHEMBL13812938 | 0.86 | GAA (0.47) | P2RX1LMNATP53MAPTKCNK3 | |
| SCHEMBL13812944 | 0.85 | KCNK3 (0.45) | MCHR1LMNATP53MAPTKCNK3 | |
| SCHEMBL13812935 | 0.85 | FADS1 (0.47) | P2RX1TP53MAPTKCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |