Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | FADS1 | O60427 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812938 | 0.93 | GAA (0.47) | FADS1P2RX1MAPTGAAKDM4E | |
| SCHEMBL13812935 | 0.90 | FADS1 (0.47) | SIRT2FADS1P2RX1MAPTGAA | |
| SCHEMBL13812943 | 0.90 | KDM4E (0.47) | FADS1MCL1MAPTGAAKDM4E | |
| SCHEMBL13812948 | 0.89 | FADS1 (0.50) | SIRT2FADS1P2RX1MAPTGAA | |
| SCHEMBL13812932 | 0.89 | MCL1 (0.48) | FADS1MCL1P2RX1MAPTGAA | |
| SCHEMBL13812946 | 0.89 | FADS1 (0.54) | SIRT2FADS1P2RX1MAPTGAA | |
| SCHEMBL13812803 | 0.88 | TRPV1 (0.50) | FADS1MAPTGAAKDM4ENPC1 | |
| SCHEMBL13812936 | 0.87 | FADS1 (0.49) | FADS1MAPTGAAKDM4ENPC1 | |
| SCHEMBL13812809 | 0.87 | POLB (0.51) | FADS1MAPTGAAKDM4ENPC1 | |
| SCHEMBL13812934 | 0.86 | KCNK3 (0.47) | FADS1KDM4ENPC1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |