Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | MAOB | P27338 | 5/20 | 0.63 |
| ▸ | MAOA | P21397 | 3/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6057426 | 0.89 | MAOB (0.69) | RAB9ANPC1MAOBMAOACA12 | |
| SCHEMBL22336400 | 0.87 | MAOB (0.61) | RAB9ANPC1MAOBMAOACYP19A1 | |
| SCHEMBL11510931 | 0.85 | RAB9A (0.65) | RAB9ANPC1MAOBMAOACA12 | |
| SCHEMBL31114416 | 0.81 | MAOB (0.79) | RAB9AMAOBMAOAGAAMAPT | |
| SCHEMBL631673 | 0.81 | MAOB (0.79) | RAB9AMAOBMAOAGAAMAPT | |
| SCHEMBL7739637 | 0.81 | MAOB (0.67) | RAB9ANPC1MAOBMAOATSHR | |
| SCHEMBL14691662 | 0.81 | MAOB (0.67) | RAB9ANPC1MAOBMAOATSHR | |
| SCHEMBL1070131 | 0.80 | NPC1 (0.73) | RAB9ANPC1MAOBMAOACA12 | |
| SCHEMBL28651037 | 0.80 | GP6 (0.55) | RAB9ANPC1FFAR1KCNA3GAA | |
| SCHEMBL11627752 | 0.80 | NPC1 (0.50) | RAB9ANPC1MAOBMAOATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |