Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | KDM4B | O94953 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | GPR6 | P46095 | 3/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2924092 | 0.86 | OPRM1 (0.44) | POLBTRPC5 | |
| SCHEMBL2926479 | 0.80 | TSHR (0.39) | POLBSMN1; SMN2KDM4AKDM4BKDM5C | |
| SCHEMBL2926584 | 0.80 | GALR3 (0.51) | POLBKDM4ESMN1; SMN2TRPC5ALDH1A1 | |
| SCHEMBL2924574 | 0.79 | POLB (0.43) | POLBKDM4ESMN1; SMN2KDM4AKDM4B | |
| SCHEMBL2918926 | 0.78 | ALDH1A1 (0.49) | KDM4EPARP1PARP2ALDH1A1KMT2A | |
| SCHEMBL2926769 | 0.77 | TRPC5 (0.43) | KDM4EKDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL2926406 | 0.77 | CA1 (0.40) | PARP1TRPC5PARP2HTR1AHTR2A | |
| SCHEMBL2926143 | 0.77 | KDM4E (0.36) | POLBKDM4ESMN1; SMN2KDM4AKDM4B | |
| SCHEMBL2925865 | 0.77 | GRIN2B (0.44) | POLBSMN1; SMN2TRPC5DRD2DRD1 | |
| SCHEMBL2925554 | 0.77 | ALDH1A1 (0.58) | KDM4ESMN1; SMN2DRD2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090149466-A1 | INHIBITORS OF STEAROYL-COA DESATURASE | GILLESPIE PAUL | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149466-A1 | INHIBITORS OF STEAROYL-COA DESATURASE | SCD, SCD5, FADS2 | POLB 3147/4885KDM4E 856/4885SMN1; SMN2 1950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.