Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297222 | 0.90 | HSD17B10 (0.44) | HSD17B10ALDH1A1ELANEALOX15ALOX12 | |
| SCHEMBL16281818 | 0.87 | ELANE (0.34) | HSD17B10ALDH1A1ELANEMAPTKMT2A | |
| SCHEMBL16542783 | 0.83 | ELANE (0.36) | HSD17B10ALDH1A1ELANEMAPTKMT2A | |
| SCHEMBL7618929 | 0.80 | GABRA1 (0.41) | HSD17B10ALDH1A1ELANETSHR | |
| SCHEMBL7620486 | 0.80 | HSD17B10 (0.37) | HSD17B10ALDH1A1ELANEALOX15ALOX12 | |
| SCHEMBL1837592 | 0.80 | HSD17B10 (0.37) | HSD17B10ALDH1A1ELANEALOX15ALOX12 | |
| SCHEMBL27710684 | 0.76 | ELANE (0.36) | HSD17B10ALDH1A1ELANEMAPTKMT2A | |
| SCHEMBL10930754 | 0.74 | HSD17B10 (0.39) | HSD17B10KMT2AATMTSHR | |
| SCHEMBL23855075 | 0.73 | HSD17B10 (0.48) | HSD17B10ALDH1A1ALOX15ALOX12MAPT | |
| SCHEMBL11482792 | 0.73 | MAPT (0.36) | HSD17B10ALDH1A1ELANEMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072577-A1 | CURABLE COMPOSITION | Kaneka Corporation (JP) | 2009-06-24 | — | — | EP | disclosed |