Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297222 | 0.80 | HSD17B10 (0.44) | HSD17B10KMT2ATSHRTDP1ATM | |
| SCHEMBL10604787 | 0.79 | TSHR (0.46) | HSD17B10KMT2ATSHRTDP1 | |
| SCHEMBL13813635 | 0.74 | HSD17B10 (0.40) | HSD17B10KMT2ATSHRATM | |
| SCHEMBL3413337 | 0.72 | THRB (0.45) | HSD17B10KMT2ATSHRTDP1 | |
| SCHEMBL10935249 | 0.71 | CYP3A4 (0.41) | HSD17B10KMT2APTPN2TSHR | |
| SCHEMBL7620486 | 0.71 | HSD17B10 (0.37) | HSD17B10KMT2ATDP1ATM | |
| SCHEMBL1837592 | 0.71 | HSD17B10 (0.37) | HSD17B10KMT2AATM | |
| SCHEMBL7618929 | 0.71 | GABRA1 (0.41) | HSD17B10TSHR | |
| SCHEMBL11169252 | 0.69 | THRB (0.47) | TSHRTDP1 | |
| SCHEMBL5704237 | 0.69 | THRB (0.49) | HSD17B10KMT2ATSHRGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60146845-A | — | — | None | — | — | JP | disclosed |
| JP-S60146845-A | (METH)ACRYLOYL SALICYLATE DERIVATIVE | NIPPON KOGAKU KK <NIKON> | 1985-08-02 | — | — | JP | disclosed |