Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1837592 | 0.91 | HSD17B10 (0.37) | HSD17B10PTGDR2ATMALDH1A1LMNA | |
| SCHEMBL297222 | 0.85 | HSD17B10 (0.44) | HSD17B10ATMALDH1A1TDP1LMNA | |
| SCHEMBL13813635 | 0.80 | HSD17B10 (0.40) | HSD17B10ATMALDH1A1LMNAMAPT | |
| SCHEMBL10864666 | 0.78 | VCAM1 (0.39) | HSD17B10ATMALDH1A1TDP1LMNA | |
| SCHEMBL674146 | 0.76 | ALDH1A1 (0.44) | HSD17B10ATMALDH1A1TDP1MAPT | |
| SCHEMBL7618929 | 0.76 | GABRA1 (0.41) | HSD17B10ALDH1A1ELANE | |
| SCHEMBL7761353 | 0.75 | PTGDR2 (0.41) | PTGDR2VCAM1 | |
| SCHEMBL30325932 | 0.75 | CA1 (0.49) | ATMALDH1A1TDP1MAPTELANE | |
| SCHEMBL15709517 | 0.74 | PTGDR2 (0.39) | HSD17B10PTGDR2ALDH1A1LMNAMAPT | |
| SCHEMBL30340743 | 0.72 | THRB (0.38) | HSD17B10PTGDR2TDP1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994844-B1 | HIGH INDEX OF REFRACTION MONOMERS | MINNESOTA MINING & MFG (US) | 2002-07-31 | — | — | EP | claimed |