Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FABP1 | P07148 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035476 | 0.80 | HSD11B1 (0.59) | HSD11B1ALDH1A1GAAPOLBLMNA | |
| SCHEMBL13886798 | 0.80 | TSHR (0.55) | ALDH1A1SMN1; SMN2TSHRGFERGAA | |
| SCHEMBL4032724 | 0.80 | TSHR (0.55) | ALDH1A1SMN1; SMN2TSHRGFERGAA | |
| SCHEMBL1384751 | 0.79 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2TP53TSHRGFER | |
| SCHEMBL4038572 | 0.79 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2TP53TSHRGFER | |
| SCHEMBL4034926 | 0.79 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2TP53TSHRGFER | |
| SCHEMBL4041537 | 0.75 | LMNA (0.53) | HSD11B1ALDH1A1TP53GAAPOLB | |
| SCHEMBL26673612 | 0.73 | ALDH1A1 (0.52) | HSD11B1ALDH1A1GAAHTT | |
| SCHEMBL4036441 | 0.72 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2TP53TSHRGFER | |
| SCHEMBL4037035 | 0.72 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2TP53TSHRGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4825664-B2 | — | — | 2011-11-30 | — | — | JP | claimed |