Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 6/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13817539 | 0.89 | NR3C2 (0.39) | CTSAFFAR1NPC1RAB9AALOX5 | |
| SCHEMBL13817542 | 0.88 | CTSA (0.41) | CTSALMNA | |
| SCHEMBL13817470 | 0.88 | IDO1 (0.42) | CTSAFFAR1MEN1KMT2ACNR2 | |
| SCHEMBL4482931 | 0.86 | CASP1 (0.39) | CTSANPC1RAB9AALOX5MEN1 | |
| SCHEMBL4506759 | 0.83 | FFAR1 (0.43) | CTSAFFAR1NPC1RAB9AMEN1 | |
| SCHEMBL4499232 | 0.82 | ALOX5 (0.38) | CTSAFFAR1NPC1RAB9AALOX5 | |
| SCHEMBL4501790 | 0.82 | L3MBTL1 (0.47) | CTSAFFAR1NPC1RAB9AALDH1A1 | |
| SCHEMBL4492518 | 0.81 | CTSA (0.44) | CTSAFFAR1NPC1RAB9AALOX5 | |
| SCHEMBL4492426 | 0.81 | FFAR1 (0.39) | CTSAFFAR1NPC1RAB9AALDH1A1 | |
| SCHEMBL4487410 | 0.81 | CTSA (0.42) | CTSAFFAR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541472-B2 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | CROPSOLUTION, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-7541472-B2 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | CROPSOLUTION, INC. (US) | 2009-06-02 | — | — | US | disclosed |