Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 8/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4499116 | 0.87 | CTSA (0.47) | CTSAMAOBALOX5MMP2MMP9 | |
| SCHEMBL4501790 | 0.85 | L3MBTL1 (0.47) | CTSAMAOBMMP12FFAR1NPC1 | |
| SCHEMBL4501448 | 0.84 | CTSA (0.41) | CTSAMAOBALOX5FFAR1 | |
| SCHEMBL4498439 | 0.83 | CTSA (0.51) | CTSAALOX5MMP2MMP9FFAR1 | |
| SCHEMBL4482931 | 0.83 | CASP1 (0.39) | CTSAALOX5LMNANPC1RAB9A | |
| SCHEMBL4492485 | 0.81 | PTPRC (0.45) | CTSAPOLBALOX5LMNANPC1 | |
| SCHEMBL4499232 | 0.81 | ALOX5 (0.38) | CTSAMAOBALOX5FFAR1NPC1 | |
| SCHEMBL13817541 | 0.81 | CTSA (0.37) | CTSAALOX5FFAR1LMNANPC1 | |
| SCHEMBL4494152 | 0.80 | CTSA (0.38) | CTSAFFAR1 | |
| SCHEMBL4498395 | 0.80 | L3MBTL1 (0.41) | CTSAPOLBLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541472-B2 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | CROPSOLUTION, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-7541472-B2 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | CROPSOLUTION, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-7541472-B2 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | CROPSOLUTION, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-20060094739-A1 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | ATP CAPITAL LP | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094739-A1 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | CYP51A1, DDT, CYP21A2 | CTSA 1423/4885GRIN2B 417/4885POLB 4306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.