Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RRM1 | P23921 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14545945 | 0.93 | HSD11B1 (0.34) | HSD11B1SLC6A4SLC6A3CASP1ALDH1A1 | |
| SCHEMBL13181479 | 0.91 | CASP1 (0.35) | SLC6A4SLC6A3CASP1ALDH1A1PTPN1 | |
| SCHEMBL10296813 | 0.85 | HSD11B1 (0.34) | HSD11B1SLC6A4SLC6A3CASP1ALDH1A1 | |
| SCHEMBL14557898 | 0.85 | CASP1 (0.38) | HSD11B1SLC6A4SLC6A3CASP1ALDH1A1 | |
| SCHEMBL13918723 | 0.84 | — | — | |
| SCHEMBL13818318 | 0.84 | HSD11B1 (0.35) | HSD11B1SLC6A4SLC6A3CASP1ALDH1A1 | |
| SCHEMBL14546136 | 0.84 | CASP1 (0.36) | SLC6A4SLC6A3CASP1ALDH1A1PTPN1 | |
| SCHEMBL12807621 | 0.83 | RRM1 (0.34) | HSD11B1SLC6A4SLC6A3CASP1ALDH1A1 | |
| SCHEMBL13181478 | 0.82 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL12807717 | 0.81 | HSD11B1 (0.36) | HSD11B1SLC6A4SLC6A3CASP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070083010-A1 | aromatic polyether with sulfonic acid-functional block and acid-free blocks; polyether sulfones; polymer electrolyte fuel cells | SUMITOMO CHEMICAL COMPANY, LIMITED | 2007-04-12 | — | — | US | disclosed |