Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | LMNA | P02545 | 5/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.74 |
| ▸ | RECQL | P46063 | 3/20 | 0.74 |
| ▸ | BLM | P54132 | 3/20 | 0.74 |
| ▸ | EGFR | P00533 | 3/20 | 0.74 |
| ▸ | HTT | P42858 | 3/20 | 0.74 |
| ▸ | USP2 | O75604 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.74 |
| ▸ | NSD2 | O96028 | 2/20 | 0.74 |
| ▸ | TOP2A | P11388 | 2/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.74 |
| ▸ | NPC1 | O15118 | 2/20 | 0.74 |
| ▸ | RAB9A | P51151 | 2/20 | 0.74 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.74 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.74 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11044463 | 0.99 | MEN1 (0.75) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4191340 | 0.99 | MEN1 (0.75) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL3917115 | 0.92 | NSD2 (0.65) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| Amentantrone SCHEMBL30390727 | 0.89 | MEN1 (0.74) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| Amentantrone SCHEMBL29580057 | 0.89 | MEN1 (0.74) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| Amentantrone SCHEMBL3273264 | 0.89 | MEN1 (0.74) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10961519 | 0.88 | NQO1 (0.69) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| Dimethylamine SCHEMBL28602840 | 0.88 | NSD2 (0.60) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL18567079 | 0.88 | TOP2B (0.86) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL29843940 | 0.87 | TOP2B (0.81) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553816-B2 | p-amidobenzylethers in drug delivery agents | SEATTLE GENETICS, INC. (US) | 2009-06-30 | — | — | US | disclosed |