Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.65 |
| ▸ | FGB | P02675 | 1/20 | 0.65 |
| ▸ | MMP14 | P50281 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | RECQL | P46063 | 4/20 | 0.60 |
| ▸ | BLM | P54132 | 3/20 | 0.60 |
| ▸ | USP2 | O75604 | 3/20 | 0.60 |
| ▸ | EGFR | P00533 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.60 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.60 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.60 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.60 |
| ▸ | CSNK2A3 | Q8NEV1 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL28602840 | 0.96 | NSD2 (0.60) | NSD2FGBMMP14MEN1KMT2A | |
| SCHEMBL4212641 | 0.92 | NSD2 (0.67) | NSD2FGBMMP14MEN1KMT2A | |
| SCHEMBL13822029 | 0.92 | MEN1 (0.74) | NSD2FGBMMP14MEN1KMT2A | |
| SCHEMBL9357997 | 0.91 | NSD2 (0.77) | NSD2FGBMMP14MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11044463 | 0.90 | MEN1 (0.75) | NSD2FGBMMP14MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4191340 | 0.90 | MEN1 (0.75) | NSD2FGBMMP14MEN1KMT2A | |
| SCHEMBL20333890 | 0.89 | NSD2 (0.69) | NSD2FGBMMP14MEN1KMT2A | |
| SCHEMBL20885913 | 0.88 | KMT2A (0.60) | NSD2FGBMMP14MEN1KMT2A | |
| SCHEMBL8428873 | 0.86 | TOP2B (0.70) | NSD2FGBMMP14MEN1KMT2A | |
| SCHEMBL4732627 | 0.86 | MEN1 (0.72) | NSD2FGBMMP14MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2705094-B1 | DISULFIDE DYES | BASF SE (DE) | 2021-12-15 | — | — | EP | disclosed |
| US-8992633-B2 | Disulfide dyes | BASF SE (DE) | 2015-03-31 | — | — | US | disclosed |
| US-20140157529-A1 | DISULFIDE DYES | BASF SE (DE) | 2014-06-12 | — | — | US | disclosed |
| EP-2705094-A1 | DISULFIDE DYES | BASF SE (DE) | 2014-03-12 | — | — | EP | disclosed |
| WO-2012150549-A1 | DISULFIDE DYES | BASF SE (DE) | 2012-11-08 | — | — | WO | disclosed |
| EP-2075036-A1 | Disulfid dyes, composition comprising them and method of dyeing hair | Ciba Holding Inc. (CH) | 2009-07-01 | — | — | EP | disclosed |
| US-7476260-B2 | Disulfide dyes, composition comprising them and method of dyeing hair | CIBA SPECIALTY CHEMICALS CORP. (US) | 2009-01-13 | — | — | US | disclosed |
| US-20080295260-A1 | Disulfide Dyes, Composition Comprising them and Method of Dyeing Hair | CIBA SPECIALTY CHEMICALS CORP. | 2008-12-04 | — | — | US | disclosed |
| EP-1750663-A2 | DISULFIDE DYES, COMPOSITION COMPRISING THEM AND METHOD OF DYEING HAIR | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005097051-A2 | DISULFIDE DYES, COMPOSITION COMPRISING THEM AND METHOD OF DYEING HAIR | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-10-20 | — | — | WO | disclosed |
| WO-2003099242-A1 | COSMETIC AGENTS CONTAINING PROTEIN DISULFIDE ISOMERASE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-12-04 | — | — | WO | disclosed |
| US-3964862-A | Process for dyeing and printing textile materials of synthetic organic fibers | CIBA-GEIGY AG (CH) | 1976-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080295260-A1 | Disulfide Dyes, Composition Comprising them and Method of Dyeing Hair | STS, CYP2S1, SQOR | NSD2 2948/4885FGB 1882/4885MMP14 2272/4885 |
| US-20140157529-A1 | DISULFIDE DYES | KRT18, COL1A1, SULT1A1 | NSD2 949/4885FGB 571/4885MMP14 4195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.