Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.74 |
| ▸ | LMNA | P02545 | 5/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.74 |
| ▸ | BLM | P54132 | 4/20 | 0.74 |
| ▸ | RECQL | P46063 | 3/20 | 0.74 |
| ▸ | NSD2 | O96028 | 3/20 | 0.74 |
| ▸ | HTT | P42858 | 3/20 | 0.74 |
| ▸ | NPC1 | O15118 | 3/20 | 0.74 |
| ▸ | RAB9A | P51151 | 3/20 | 0.74 |
| ▸ | USP2 | O75604 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.74 |
| ▸ | TOP2A | P11388 | 2/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.74 |
| ▸ | MTOR | P42345 | 2/20 | 0.74 |
| ▸ | EGFR | P00533 | 2/20 | 0.74 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.74 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amentantrone SCHEMBL30390727 | 1.00 | MEN1 (0.74) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| Amentantrone SCHEMBL3273264 | 1.00 | MEN1 (0.74) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL20885913 | 0.92 | KMT2A (0.60) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL13822029 | 0.89 | MEN1 (0.74) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4191340 | 0.88 | MEN1 (0.75) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11044463 | 0.88 | MEN1 (0.75) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL18567079 | 0.88 | TOP2B (0.86) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| Mitoxantrone SCHEMBL187688 | 0.86 | MEN1 (0.84) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| Mitoxantrone SCHEMBL20214110 | 0.86 | MEN1 (1.00) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL11036806 | 0.86 | MEN1 (1.00) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11300575-B2 | Biomarkers and methods for measuring and monitoring inflammatory disease activity | LABORATORY CORPORATION OF AMERICA HOLDINGS (US) | 2022-04-12 | — | — | US | claimed |
| WO-2025233526-A1 | MITOCHONDRIAL COMPLEX I MODULATOR FOR USE IN THE TREATMENT OF ARTHRITIS | ISTESSO THERAPEUTICS LIMITED (GB) | 2025-11-13 | — | — | WO | disclosed |
| EP-4647071-A1 | MITOCHONDRIAL COMPLEX I MODULATOR FOR USE IN THE TREATMENT OF ARTHRITIS | Istesso Therapeutics Limited (GB) | 2025-11-12 | — | — | EP | disclosed |
| EP-3356832-B1 | BIOMARKERS AND METHODS FOR ASSESSING PSORIATIC ARTHRITIS DISEASE ACTIVITY | UNIV CALIFORNIA (US) | 2025-09-10 | — | — | EP | disclosed |
| US-12385912-B2 | Methods of treatment of arthritic disorders | LABORATORY CORPORATION OF AMERICA HOLDINGS (US) | 2025-08-12 | — | — | US | disclosed |
| CN-120164323-A | Traffic flow prediction method based on multi-time space diagram fusion and dynamic attention | 南通大学 | 2025-06-17 | — | — | CN | disclosed |
| US-20250172558-A1 | BIOMARKERS AND METHODS FOR ASSESSING PSORIATIC ARTHRITIS DISEASE ACTIVITY | LABORATORY CORPORATION OF AMERICA HOLDINGS (US) | 2025-05-29 | — | — | US | disclosed |
| US-20250172556-A1 | BIOMARKERS AND METHODS FOR ASSESSING RESPONSE TO INFLAMMATORY DISEASE THERAPY WITHDRAWAL | LABORATORY CORPORATION OF AMERICA HOLDINGS (US) | 2025-05-29 | — | — | US | disclosed |
| CN-119694528-A | Classification method and classification device thereof | 纬创资通股份有限公司 | 2025-03-25 | — | — | CN | disclosed |
| US-20250078957-A1 | Unsupervised Machine Learning Methods | AMPEL BIOSOLUTIONS LLC (US) | 2025-03-06 | — | — | US | disclosed |
| EP-4479973-A1 | UNSUPERVISED MACHINE LEARNING METHODS | Ampel Biosolutions, LLC (US) | 2024-12-25 | — | — | EP | disclosed |
| EP-4392901-A1 | LOW-LATENCY CAPTIONING SYSTEM | Mitsubishi Electric Corporation (JP) | 2024-07-03 | — | — | EP | disclosed |
| WO-2024029229-A1 | LOW-LATENCY CAPTIONING SYSTEM | MITSUBISHI ELECTRIC CORPORATION (JP) | 2024-02-08 | — | — | WO | disclosed |
| EP-4256531-A1 | LOW-LATENCY CAPTIONING SYSTEM | Mitsubishi Electric Corporation (JP) | 2023-10-11 | — | — | EP | disclosed |
| WO-2023158713-A1 | UNSUPERVISED MACHINE LEARNING METHODS | AMPEL BIOSOLUTIONS, LLC (US) | 2023-08-24 | — | — | WO | disclosed |
| US-11656227-B2 | Biomarkers and methods for assessing psoriatic arthritis disease activity | LABORATORY CORPORATION OF AMERICA HOLDINGS | 2023-05-23 | — | — | US | disclosed |
| WO-2023002745-A1 | LOW-LATENCY CAPTIONING SYSTEM | MITSUBISHI ELECTRIC CORPORATION (JP) | 2023-01-26 | — | — | WO | disclosed |
| US-20220381795-A1 | Biomarkers and Methods for Measuring and Monitoring Inflammatory Disease Activity | LABORATORY CORPORATION OF AMERICA HOLDINGS (US) | 2022-12-01 | — | — | US | disclosed |
| US-20220214341-A1 | BIOMARKERS AND METHODS FOR ASSESSING PSORIATIC ARTHRITIS DISEASE ACTIVITY | LABORATORY CORPORATION OF AMERICA HOLDINGS | 2022-07-07 | — | — | US | disclosed |
| US-11300575-B2 | Biomarkers and methods for measuring and monitoring inflammatory disease activity | LABORATORY CORPORATION OF AMERICA HOLDINGS (US) | 2022-04-12 | — | — | US | disclosed |