Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.74 |
| ▸ | LMNA | P02545 | 5/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.74 |
| ▸ | BLM | P54132 | 4/20 | 0.74 |
| ▸ | RECQL | P46063 | 3/20 | 0.74 |
| ▸ | NSD2 | O96028 | 3/20 | 0.74 |
| ▸ | HTT | P42858 | 3/20 | 0.74 |
| ▸ | NPC1 | O15118 | 3/20 | 0.74 |
| ▸ | RAB9A | P51151 | 3/20 | 0.74 |
| ▸ | USP2 | O75604 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.74 |
| ▸ | TOP2A | P11388 | 2/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.74 |
| ▸ | MTOR | P42345 | 2/20 | 0.74 |
| ▸ | EGFR | P00533 | 2/20 | 0.74 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.74 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amentantrone SCHEMBL29580057 | 1.00 | MEN1 (0.74) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| Amentantrone SCHEMBL3273264 | 1.00 | MEN1 (0.74) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL20885913 | 0.92 | KMT2A (0.60) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL13822029 | 0.89 | MEN1 (0.74) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4191340 | 0.88 | MEN1 (0.75) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11044463 | 0.88 | MEN1 (0.75) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL18567079 | 0.88 | TOP2B (0.86) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| Mitoxantrone SCHEMBL187688 | 0.86 | MEN1 (0.84) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| Mitoxantrone SCHEMBL20214110 | 0.86 | MEN1 (1.00) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL11036806 | 0.86 | MEN1 (1.00) | MEN1KMT2ALMNAMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260102541-A1 | METHODS OF MAKING THERAPEUTIC POLYMERIC MATERIAL | MASSACHUSETTS GEN HOSPITAL (US) | 2026-04-16 | — | — | US | disclosed |
| US-20250302768-A1 | NANOPARTICLE DOPED POLYETHYLENE GLYCOL BASED GELS AND MEDICAL DEVICES FOR DRUG DELIVERY | THE GENERAL HOSPITAL CORPORATION | 2025-10-02 | — | — | US | disclosed |
| US-12350403-B2 | Methods of making therapeutic polymeric material | THE GENERAL HOSPITAL CORPORATION (US) | 2025-07-08 | — | — | US | disclosed |
| WO-2023220717-A2 | NANOPARTICLE DOPED POLYETHYLENE GLYCOL BASED GELS AND MEDICAL DEVICES FOR DRUG DELIVERY | THE GENERAL HOSPITAL CORPORATION (US) | 2023-11-16 | — | — | WO | disclosed |
| US-20230190655-A1 | METHODS FOR CONSOLIDATING ANTIBIOTIC-ELUTING POLYMERIC MATERIALS | THE GENERAL HOSPITAL CORPORATION | 2023-06-22 | — | — | US | disclosed |
| US-11667762-B2 | UV-initiated reactions in polymeric materials | THE GENERAL HOSPITAL CORPORATION (US) | 2023-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260102541-A1 | METHODS OF MAKING THERAPEUTIC POLYMERIC MATERIAL | UBE2L6, EIF3E, UROD | MEN1 2232/4885KMT2A 4317/4885LMNA 1398/4885 |
| US-20230190655-A1 | METHODS FOR CONSOLIDATING ANTIBIOTIC-ELUTING POLYMERIC MATERIALS | PUF60, ALG1, PCBP1 | MEN1 1889/4885KMT2A 2801/4885LMNA 3020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.