Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11789735 | 0.85 | TSHR (0.57) | TSHRKDM4ECLEC4MALDH1A1TDP1 | |
| SCHEMBL4081935 | 0.85 | CLEC4M (0.57) | TSHRKDM4ECLEC4MKMT2AATM | |
| SCHEMBL536590 | 0.83 | KDM4E (0.46) | TSHRKDM4EHTTKMT2AATM | |
| Potassium SCHEMBL29729324 | 0.81 | KDM4E (0.45) | TSHRKDM4EHTTKMT2AATM | |
| SCHEMBL6016867 | 0.81 | CLEC4M (0.40) | KDM4EHTTCLEC4MKMT2AATM | |
| Acetic Acid SCHEMBL27464432 | 0.79 | KDM4E (0.43) | TSHRKDM4EHTTKMT2AATM | |
| SCHEMBL1382494 | 0.78 | TSHR (0.56) | TSHRBRD4 | |
| SCHEMBL6016899 | 0.77 | CHRNB2 (0.39) | CLEC4M | |
| SCHEMBL2646903 | 0.75 | PARP1 (0.41) | KDM4EHTTKMT2AALDH1A1TDP1 | |
| SCHEMBL29389335 | 0.74 | TSHR (1.00) | TSHRKDM4EKMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4658940-B2 | — | — | 2011-03-23 | — | — | JP | claimed |
| JP-2006528213-A | — | — | 2006-12-14 | — | — | JP | claimed |
| EP-1636216-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-22 | — | — | EP | claimed |
| WO-2004101553-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | claimed |