SCHEMBL4081935

SCHEMBL4081935

CCOC(=O)c1cccc2nc[nH]c12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CLEC4M Q9H2X3 1/20 0.57
TSHR P16473 1/20 0.53
KMT2A Q03164 3/20 0.50
ATM Q13315 1/20 0.50
ALDH1A1 P00352 3/20 0.46
HSD17B10 Q99714 2/20 0.46
KDM4E B2RXH2 3/20 0.46
CYP1A2 P05177 1/20 0.45
NUDT1 P36639 1/20 0.45
ALK Q9UM73 1/20 0.45
CDC25B P30305 1/20 0.43
BRAF P15056 1/20 0.43
NPC1 O15118 1/20 0.43
TP53 P04637 1/20 0.43
HPGD P15428 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11789735 0.86 TSHR (0.57) CLEC4MTSHRALDH1A1HSD17B10KDM4E
SCHEMBL1382500 0.85 TSHR (0.56) CLEC4MTSHRKMT2AATMALDH1A1
SCHEMBL6016867 0.84 CLEC4M (0.40) CLEC4MKMT2AATMALDH1A1HSD17B10
SCHEMBL536590 0.83 KDM4E (0.46) TSHRKMT2AATMALDH1A1HSD17B10
Potassium SCHEMBL29729324 0.82 KDM4E (0.45) TSHRKMT2AATMALDH1A1HSD17B10
SCHEMBL6016899 0.81 CHRNB2 (0.39) CLEC4M
SCHEMBL4907504 0.80 KMT2A (0.46) CLEC4MTSHRKMT2AATMALDH1A1
Hydrochloric Acid SCHEMBL4914364 0.79 KMT2A (0.45) CLEC4MTSHRKMT2AATMALDH1A1
SCHEMBL2646903 0.78 PARP1 (0.41) KMT2AALDH1A1KDM4ENPC1HPGD
SCHEMBL13961675 0.77 KDM4E (0.43) TSHRKMT2AATMALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120005091-A Temperature-resistant and salt-resistant polymer oil displacement agent and preparation method thereof 东营科创生物化工有限公司 2025-05-16 CN claimed
CN-113466360-B Azilsartan 6 related substance detection method 珠海润都制药股份有限公司 2023-03-03 CN claimed
CN-120005091-A Temperature-resistant and salt-resistant polymer oil displacement agent and preparation method thereof 东营科创生物化工有限公司 2025-05-16 CN disclosed
CN-119644685-A High-efficiency positive photoresist stripping solution and preparation method thereof 浙江尚能实业股份有限公司 2025-03-18 CN disclosed
CN-112898287-B Preparation method of azilsartan 江苏中邦制药有限公司 2024-08-30 CN disclosed
CN-113466360-B Azilsartan 6 related substance detection method 珠海润都制药股份有限公司 2023-03-03 CN disclosed
EP-1697343-B1 AMINOBENZIMIDAZOLES AND BENZIMIDAZOLES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION TIBOTEC PHARM LTD (IE) 2009-07-01 EP disclosed
WO-1995003298-A1 BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-02-02 WO disclosed
US-3988155-A CYANINE SENSITIZING DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-10-26 US disclosed
US-3985563-A Silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-10-12 US disclosed