Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PAM | P19021 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4081935 | 0.84 | CLEC4M (0.57) | CLEC4MCYP1A2KMT2AALDH1A1KDM4E | |
| SCHEMBL1382500 | 0.81 | TSHR (0.56) | CLEC4MKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL11789735 | 0.80 | TSHR (0.57) | CLEC4MCYP1A2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL6016899 | 0.80 | CHRNB2 (0.39) | CLEC4M | |
| SCHEMBL536590 | 0.79 | KDM4E (0.46) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL453513 | 0.78 | KEAP1 (0.49) | KMT2AALDH1A1KDM4EHTTALOX15 | |
| Potassium SCHEMBL29729324 | 0.78 | KDM4E (0.45) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6016863 | 0.77 | PARP1 (0.57) | PARP1 | |
| Hydrochloric Acid SCHEMBL22165595 | 0.77 | KEAP1 (0.47) | KMT2AALDH1A1KDM4EHTTALOX15 | |
| SCHEMBL5990597 | 0.77 | KEAP1 (0.47) | KMT2AALDH1A1KDM4EHTTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004101553-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |