Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4081935 | 0.81 | CLEC4M (0.57) | CLEC4M | |
| SCHEMBL6016867 | 0.80 | CLEC4M (0.40) | CLEC4M | |
| SCHEMBL6016896 | 0.79 | PARP1 (0.57) | — | |
| SCHEMBL1382500 | 0.77 | TSHR (0.56) | CLEC4M | |
| SCHEMBL11789735 | 0.76 | TSHR (0.57) | CLEC4M | |
| SCHEMBL536590 | 0.76 | KDM4E (0.46) | — | |
| Potassium SCHEMBL29729324 | 0.75 | KDM4E (0.45) | — | |
| SCHEMBL453513 | 0.72 | KEAP1 (0.49) | — | |
| SCHEMBL2509536 | 0.71 | SLC6A2 (0.39) | — | |
| SCHEMBL9087577 | 0.71 | CHRNB2 (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004101553-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |