SCHEMBL138254

SCHEMBL138254

CC(C)(C)c1cccc(C(C)(C)C)c1N

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.55
GABRA1 P14867 1/20 0.46
GABRB2 P47870 1/20 0.46
ALDH1A1 P00352 3/20 0.46
TSHR P16473 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
KIF11 P52732 1/20 0.39
ALOX12 P18054 1/20 0.38
CD44 P16070 1/20 0.36
CYP3A4 P08684 2/20 0.35
PIK3CA P42336 1/20 0.35
POLB P06746 1/20 0.35
NPSR1 Q6W5P4 1/20 0.34
ALOX15 P16050 2/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9861588 0.88 CA2 (0.44) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL6028201 0.87 CD44 (0.48) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL1804107 0.85 GABRA1 (0.56) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL30154643 0.85 GABRA1 (0.56) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL1530406 0.83 CA2 (0.44) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL29470930 0.83 CA2 (0.44) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL144361 0.83 ALDH1A1 (0.60) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL3786915 0.83 CA2 (0.44) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL19119512 0.81 CA2 (0.39) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL4729184 0.81 CA2 (0.43) CA2GABRA1GABRB2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 545 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115028583-B Super-crosslinking N-heterocyclic carbene imidazolium salt ligand, and preparation method and application thereof 中国科学院青岛生物能源与过程研究所 2023-10-24 CN claimed
CN-115028583-A Hypercrosslinked N-heterocyclic carbene imidazolium salt ligand, preparation method and application thereof 中国科学院青岛生物能源与过程研究所 2022-09-09 CN claimed
CN-113651701-A High-heat-resistance aromatic diamine organic matter and preparation method thereof 艾蒙特成都新材料科技有限公司 2021-11-16 CN claimed
EP-1701793-B1 A CATALYST SYSTEM FOR ETHYLENE (CO)-POLYMERIZATION FORMOSA PLASTICS CORP USA (US) 2017-06-28 EP claimed
CN-102633840-A Clamp-type iron complex and preparation method and application thereof UNIV JILIN 2012-08-15 CN claimed
EP-1701793-A4 A CATALYST SYSTEM FOR ETHYLENE (CO)-POLYMERIZATION FORMOSA PLASTICS CORP USA (US) 2008-07-16 EP claimed
EP-1701793-A1 A CATALYST SYSTEM FOR ETHYLENE (CO)-POLYMERIZATION Formosa Plastics Corporation, U.S.A. (US) 2006-09-20 EP claimed
US-6956003-B2 Catalyst system for ethylene (co)-polymerization FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2005-10-18 US claimed
WO-2005061109-A1 A CATALYST SYSTEM FOR ETHYLENE (CO)-POLYMERIZATION FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2005-07-07 WO claimed
US-20050124488-A1 Catalyst system for ethylene (co)-polymerization FORMOSA PLASTICS CORPORATION, USA 2005-06-09 US claimed
EP-3670551-B1 COPOLYMER, RUBBER COMPOSITION, RUBBER COMPOSITION FOR TIRE SIDE USE, CROSSLINKED RUBBER COMPOSITION AND TIRE BRIDGESTONE CORP (JP) 2026-05-13 EP disclosed
US-12559581-B2 Ethylene-copolymers and catalyst mixture for making ethylene copolymers ARLANXEO NETHERLANDS B.V. (NL) 2026-02-24 US disclosed
EP-3722339-B1 COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT BRIDGESTONE CORP (JP) 2025-07-30 EP disclosed
EP-4330297-B1 METAL COMPLEX CATALYST FOR THE POLYMERIZATION OF OLEFINS Arlanxeo Netherlands Bv (NL) 2025-07-30 EP disclosed
EP-3722337-B1 COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT BRIDGESTONE CORP (JP) 2025-07-30 EP disclosed
EP-0053818-B1 PROCESS FOR THE PREPARATION OF CYCLOHEXYL AMINES BY HYDROGENATION OF AROMATIC AMINES BASF Aktiengesellschaft (DE) 1985-05-08 EP disclosed
EP-0053818-A1 Process for the preparation of cyclohexyl amines by hydrogenation of aromatic amines BASF Aktiengesellschaft (DE) 1982-06-16 EP disclosed
EP-0003304-A2 Process for the preparation of N-substituted 2,6-dialkyl anilines BASF Aktiengesellschaft (DE) 1979-08-08 EP disclosed
US-4080307-A AMMONIUM SALTS OF 1,3-OXA- OR 1,3-THIA-PHOSPHETANES CIBA-GEIGY AG (CH) 1978-03-21 US disclosed
US-3965182-A Preparation of aniline from phenol and ammonia ETHYL CORPORATION (US) 1976-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559581-B2 Ethylene-copolymers and catalyst mixture for making ethylene copolymers EEF1D, COG7, CCND1 CA2 4353/4885GABRA1 2962/4885GABRB2 2972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.