Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.42 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.42 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1912174 | 0.93 | SMYD3 (0.58) | L3MBTL1SMYD3SMN1; SMN2LMNAHTT | |
| SCHEMBL13818620 | 0.92 | L3MBTL1 (0.46) | L3MBTL1SMYD3SMN1; SMN2LMNAHTT | |
| SCHEMBL1109491 | 0.88 | NPC1 (0.52) | L3MBTL1SMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL1109204 | 0.88 | DRD4 (0.48) | L3MBTL1SMYD3SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1109140 | 0.87 | NPC1 (0.51) | L3MBTL1SMN1; SMN2HTTALDH1A1TDP1 | |
| SCHEMBL1109363 | 0.87 | NPC1 (0.51) | L3MBTL1SMN1; SMN2HTTALDH1A1TDP1 | |
| SCHEMBL10285902 | 0.87 | L3MBTL1 (0.41) | L3MBTL1SMYD3SMN1; SMN2LMNAHTT | |
| SCHEMBL1109391 | 0.85 | ATM (0.51) | SMN1; SMN2LMNAALDH1A1TDP1KDM4E | |
| SCHEMBL1109490 | 0.85 | CTSK (0.42) | L3MBTL1SMN1; SMN2HTTALDH1A1TDP1 | |
| SCHEMBL1109173 | 0.85 | ATM (0.51) | SMN1; SMN2LMNAALDH1A1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163496-A1 | ANTIBACTERIAL AGENTS | UNIVERSITY OF WASHINGTON (US) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163496-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, PGLS | L3MBTL1 2665/4885SMYD3 4769/4885SMN1; SMN2 2296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.