Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 2/20 | 0.37 |
| ▸ | FNTB | P49356 | 2/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17675709 | 0.91 | SLC6A9 (0.47) | MEN1KMT2ASLC6A9KCNH2SLC22A1 | |
| SCHEMBL13827329 | 0.84 | SLC6A9 (0.67) | MEN1KMT2ASLC6A9KCNH2LMNA | |
| SCHEMBL13737074 | 0.77 | SLC6A9 (0.69) | MEN1KMT2ASLC6A9KCNH2LMNA | |
| SCHEMBL13827337 | 0.76 | SLC6A9 (0.57) | MEN1KMT2ASLC6A9KCNH2LMNA | |
| SCHEMBL13827792 | 0.76 | SLC6A9 (0.57) | MEN1KMT2ASLC6A9KCNH2LMNA | |
| SCHEMBL17675751 | 0.76 | SLC6A9 (0.56) | MEN1KMT2ASLC6A9KCNH2LMNA | |
| SCHEMBL15133291 | 0.75 | KMT2A (1.00) | MEN1KMT2ASLC6A9FNTAFNTB | |
| SCHEMBL13827334 | 0.74 | SLC6A9 (0.51) | MEN1KMT2ASLC6A9KCNH2LMNA | |
| SCHEMBL13738539 | 0.73 | SLC6A9 (0.64) | MEN1KMT2ASLC6A9KCNH2LMNA | |
| SCHEMBL17675759 | 0.72 | SLC6A9 (0.53) | MEN1KMT2ASLC6A9KCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309200-B2 | Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-04-12 | — | — | US | disclosed |
| US-9309200-B2 | Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-04-12 | — | — | US | disclosed |