Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 11/20 | 0.41 |
| ▸ | FNTB | P49356 | 11/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 8/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17675708 | 0.91 | MEN1 (0.57) | SLC6A9MEN1KMT2AKCNH2FNTA | |
| SCHEMBL13827329 | 0.83 | SLC6A9 (0.67) | SLC6A9MEN1KMT2AKCNH2 | |
| SCHEMBL13737074 | 0.76 | SLC6A9 (0.69) | SLC6A9MEN1KMT2AKCNH2 | |
| SCHEMBL13827792 | 0.76 | SLC6A9 (0.57) | SLC6A9MEN1KMT2AKCNH2 | |
| SCHEMBL13827337 | 0.76 | SLC6A9 (0.57) | SLC6A9MEN1KMT2AKCNH2 | |
| SCHEMBL17675751 | 0.75 | SLC6A9 (0.56) | SLC6A9MEN1KMT2AKCNH2 | |
| SCHEMBL13827334 | 0.74 | SLC6A9 (0.51) | SLC6A9MEN1KMT2AKCNH2 | |
| SCHEMBL13738539 | 0.72 | SLC6A9 (0.64) | SLC6A9MEN1KMT2AKCNH2 | |
| SCHEMBL13827331 | 0.72 | SLC6A9 (0.52) | SLC6A9MEN1KMT2ASLC22A1PRCP | |
| SCHEMBL17675759 | 0.71 | SLC6A9 (0.53) | SLC6A9MEN1KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309200-B2 | Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-04-12 | — | — | US | disclosed |
| US-9309200-B2 | Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-04-12 | — | — | US | disclosed |