Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383122 | 0.93 | F10 (0.60) | F10 | |
| SCHEMBL1379173 | 0.87 | F10 (0.57) | F10CNR1CA1CA2CA9 | |
| SCHEMBL1381539 | 0.85 | F10 (0.59) | F10ALDH1A1SMN1; SMN2 | |
| SCHEMBL6181035 | 0.84 | F10 (0.60) | F10CNR1KDM4EALDH1A1MAPT | |
| SCHEMBL8324993 | 0.83 | F10 (0.59) | F10ALDH1A1 | |
| SCHEMBL6179994 | 0.83 | F10 (0.59) | F10CNR1CA1CA2CA9 | |
| SCHEMBL1380646 | 0.79 | F10 (0.62) | F10MAPT | |
| SCHEMBL1679321 | 0.79 | F10 (0.65) | F10 | |
| SCHEMBL6182831 | 0.78 | F10 (0.59) | F10MAPTSMN1; SMN2 | |
| SCHEMBL1380603 | 0.78 | F10 (0.59) | F10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4699985-B2 | — | — | 2011-06-15 | — | — | JP | claimed |
| EP-1585730-A1 | CARBOXAMIDE DERIVATIVES AND THEIR USE AS FACTOR XA INHIBITORS | MERCK PATENT GmbH (DE) | 2005-10-19 | — | — | EP | claimed |
| WO-2004065369-A1 | CARBOXAMIDE DERIVATIVES AND THEIR USE AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2004-08-05 | — | — | WO | claimed |