Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.76 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.76 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.76 |
| ▸ | CBS | P35520 | 2/20 | 0.60 |
| ▸ | BCL9 | O00512 | 7/20 | 0.59 |
| ▸ | CTNNB1 | P35222 | 7/20 | 0.59 |
| ▸ | KLK1 | P06870 | 1/20 | 0.56 |
| ▸ | KLK3 | P07288 | 1/20 | 0.56 |
| ▸ | KLK2 | P20151 | 1/20 | 0.56 |
| ▸ | KLK7 | P49862 | 1/20 | 0.56 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.56 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morelloflavone SCHEMBL615093 | 0.86 | PRSS1 (1.00) | PRSS1PRSS2PRSS3CBSKLK1 | |
| Morelloflavone SCHEMBL2383075 | 0.86 | PRSS1 (1.00) | PRSS1PRSS2PRSS3CBSKLK1 | |
| SCHEMBL27165462 | 0.83 | PRSS1 (0.90) | PRSS1PRSS2PRSS3CBSKLK1 | |
| Volkensiflavone SCHEMBL27160551 | 0.82 | PRSS1 (0.89) | PRSS1PRSS2PRSS3CBSKLK1 | |
| Volkensiflavone SCHEMBL13829450 | 0.82 | PRSS1 (0.89) | PRSS1PRSS2PRSS3CBSKLK1 | |
| Volkensiflavone SCHEMBL7620161 | 0.82 | PRSS1 (0.89) | PRSS1PRSS2PRSS3CBSKLK1 | |
| (+)-Taxifolin SCHEMBL28059826 | 0.75 | MEN1 (0.67) | PRSS1PRSS2PRSS3BCL9CTNNB1 | |
| SCHEMBL13836467 | 0.74 | CBS (0.51) | PRSS1PRSS2PRSS3CBSBCL9 | |
| SCHEMBL6360284 | 0.73 | KLK1 (0.72) | PRSS1PRSS2PRSS3CBSKLK1 | |
| SCHEMBL16263265 | 0.73 | KLK1 (0.72) | PRSS1PRSS2PRSS3CBSKLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9296717-B2 | Synthesis of C-3 coupled biflavonoids and C-3 coupled biflavonoid analogues | UNIVERSITY OF THE FREE STATE (ZA) | 2016-03-29 | — | — | US | disclosed |
| US-9296717-B2 | Synthesis of C-3 coupled biflavonoids and C-3 coupled biflavonoid analogues | UNIVERSITY OF THE FREE STATE (ZA) | 2016-03-29 | — | — | US | disclosed |
| US-20120289715-A1 | Synthesis of C-3 Coupled Biflavonoids and C-3 Coupled Biflavonoid Analogues | UNIVERSITY OF THE FREE STATE (ZA) | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289715-A1 | Synthesis of C-3 Coupled Biflavonoids and C-3 Coupled Biflavonoid Analogues | CBR3, C9, PROC | PRSS1 3830/4885PRSS2 4528/4885PRSS3 2352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.