Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13729538 | 0.83 | DYRK1A (0.43) | KMT2AHPGDMEN1TLR8ESR2 | |
| SCHEMBL24916401 | 0.78 | P2RX3 (0.42) | KMT2AHPGDMEN1KDM4EALDH1A1 | |
| SCHEMBL4656639 | 0.77 | PDE10A (0.49) | KMT2AMEN1KDM4EALDH1A1GAA | |
| SCHEMBL10331766 | 0.75 | ALDH1A1 (0.55) | KMT2AHPGDMEN1TP53TLR8 | |
| SCHEMBL28660516 | 0.74 | EGLN1 (0.47) | ACHESLC6A2GAATHRBTDP1 | |
| SCHEMBL4813692 | 0.74 | HSD17B10 (0.52) | KMT2AHPGDMEN1KDM4EALDH1A1 | |
| SCHEMBL14543177 | 0.74 | SMN1; SMN2 (0.53) | KMT2AHPGDMEN1KDM4EALDH1A1 | |
| SCHEMBL1563993 | 0.71 | IDO1 (0.46) | HPGDKDM4EALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL13652181 | 0.70 | KDM4E (0.49) | KMT2AHPGDMEN1KDM4EALDH1A1 | |
| Formic Acid SCHEMBL28482955 | 0.69 | EGLN1 (0.46) | ACHESLC6A2GAATHRBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151195-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-11-08 | — | — | WO | disclosed |