Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.42 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916397 | 0.83 | P2RX3 (0.42) | P2RX3P2RX2DYRK1AACHEKDM4E | |
| SCHEMBL24916396 | 0.82 | DYRK1A (0.41) | P2RX3P2RX2DYRK1AKDM4EALDH1A1 | |
| SCHEMBL13829985 | 0.78 | KMT2A (0.43) | DYRK1AACHEKDM4EMAOAALDH1A1 | |
| SCHEMBL18101005 | 0.76 | MAOA (0.44) | DYRK1AKDM4EMAOAHSD17B10HPGD | |
| SCHEMBL19237536 | 0.74 | RAB9A (0.43) | P2RX3P2RX2DYRK1AACHEKDM4E | |
| SCHEMBL24916399 | 0.73 | CYP11B2 (0.49) | P2RX3P2RX2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24842479 | 0.73 | P2RX3 (0.40) | P2RX3P2RX2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL14543177 | 0.72 | SMN1; SMN2 (0.53) | DYRK1AACHEKDM4EMAOAALDH1A1 | |
| SCHEMBL12197723 | 0.72 | CYP2A6 (0.42) | P2RX3P2RX2KDM4ECYP1A2CYP3A4 | |
| SCHEMBL24391769 | 0.72 | ALDH1A1 (0.39) | P2RX3P2RX2KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | P2RX3 3671/4885P2RX2 3727/4885DYRK1A 2337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.