Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3659732 | 0.83 | MTNR1A (0.51) | MTNR1AMTNR1BNLRP3LOXL2GSK3B | |
| SCHEMBL17327742 | 0.82 | NLRP3 (0.60) | MTNR1AMTNR1BNLRP3LOXL2GSK3B | |
| SCHEMBL3654751 | 0.82 | LOXL2 (0.50) | MTNR1AMTNR1BNLRP3LOXL2GSK3B | |
| SCHEMBL1381253 | 0.81 | LOXL2 (0.53) | MTNR1AMTNR1BNLRP3LOXL2GSK3B | |
| SCHEMBL3657832 | 0.78 | MTNR1A (0.46) | MTNR1AMTNR1BNLRP3LOXL2GSK3B | |
| SCHEMBL31514826 | 0.77 | LOXL2 (0.55) | MTNR1AMTNR1BNLRP3LOXL2GSK3B | |
| SCHEMBL3120573 | 0.77 | MTNR1A (0.60) | MTNR1AMTNR1BNLRP3LOXL2GSK3B | |
| SCHEMBL3451201 | 0.76 | LOXL2 (0.58) | MTNR1AMTNR1BNLRP3LOXL2GSK3B | |
| SCHEMBL8686875 | 0.76 | MTNR1A (0.56) | MTNR1AMTNR1BNLRP3LOXL2GSK3B | |
| SCHEMBL49270 | 0.75 | LOXL2 (0.56) | MTNR1AMTNR1BNLRP3LOXL2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4803935-B2 | — | — | 2011-10-26 | — | — | JP | claimed |